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The South African Pharmaceutical Exhibition (SAPHEX) is scheduled for March 5-6, 2025, at the Sandton Convention Centre in Johannesburg.


SAPHEX stands as the premier event for professionals in South Africa's pharmaceutical manufacturing industry. The exhibition brings together key players, decision-makers, and suppliers, showcasing the latest innovations in APIs, excipients, packaging, and machinery. Attendees can expect to network, explore new advancements, and engage in discussions pivotal to the growth of the African pharmaceutical market.


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SAMRC and DFFE Partnership Turns Air Pollution Into a National Public-Health Priority

The South African Medical Research Council and the Department of Forestry, Fisheries and the Environment have signed a new Memorandum of Understanding to strengthen research, policy and public-health action on the impact of air pollution in South Africa. Announced on 5 July 2026, the agreement will bring environmental and health experts closer together through joint work on research, health-impact assessments, data sharing, air-quality monitoring, policy development and public-awareness initiatives. The partnership is important because air pollution is not only an environmental concern; it is linked to serious health risks including respiratory disease, cardiovascular disease, stroke, cancer and premature death, with communities near industrial areas, power-generation facilities, transport corridors and informal settlements often carrying the heaviest burden. By combining the DFFE's environmental-management role with the SAMRC's public-health and epidemiology expertise, the collaboration aims to generate stronger evidence for cleaner-air policies, better early-warning systems and targeted interventions that protect vulnerable communities during periods of poor air quality. The move also reflects a wider global concern, with WHO warning that low- and middle-income countries continue to face higher exposure to harmful air pollution and a greater disease burden. In practical terms, the MoU signals a shift toward treating clean air as a health right, not a luxury - and toward using science to prevent illness before polluted air becomes hospital admissions, chronic disease and early death.





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Heartburn Medications Linked to Increased Depression Risk, Experts Warn

Millions of people in the UK taking common heartburn medications may face an increased risk of developing depression, experts have cautioned. Proton pump inhibitors (PPIs), such as omeprazole and lansoprazole, which are used to reduce stomach acid, were prescribed more than 74 million times in England in 2023. PPIs can interfere with the absorption of vitamin B12, a critical nutrient for maintaining mental health. The NHS acknowledges that a deficiency in vitamin B12 can result in psychological issues such as depression, confusion, and even dementia. �PPIs can block 80% or more of stomach acid production, which significantly impacts nutrient absorption,� explained pharmacist Deborah Grayson. This disruption can hinder the body�s ability to produce serotonin, often referred to as the "happy hormone," potentially leading to low mood or depression. A 2017 study involving around 350 elderly participants suggested that one-sixth of depression cases could be linked to PPI use. Product leaflets for PPIs already caution users to seek medical advice if they experience symptoms like memory problems, confusion, or depression. Other medications, including certain antibiotics such as ciprofloxacin and levofloxacin, have also been associated with mood disorders. These antibiotics may affect mood by disrupting the gut microbiome, which plays a role in producing brain hormones. Additionally, drugs like topiramate (Topamax) and gabapentin (Neurontin), prescribed for epilepsy and nerve pain, have been linked to mood changes and depression in a small percentage of patients. Experts stress that patients should not discontinue their medications without consulting a healthcare professional. Instead, they should seek medical advice to address symptoms of depression, including a review of vitamin B12 and folate levels. Immediate medical attention is recommended for severe symptoms such as suicidal thoughts. For those experiencing depression for more than two weeks, particularly if it interferes with daily life, the NHS advises consulting a GP for appropriate treatment.








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